@xWiNiMx Do you mean MSI MS-16R3?
At a glance it looks like they could be more or less interchangeable, but that's a pretty invasive procedure and it would be more or less impossible to know for sure how it would work out for your specific system without giving it a try. If you're paying some of the prices I'm seeing online, I would question the risk v. reward. Otherwise, let us know how it works out!
I wouldn't say its taboo, though it is uncommon. I've seen plenty of people on the NotebookReview forum perform swaps like these in Clevo based models with great success. The big things to keep in mind are whether the board's monitor pinout matches that of your panel (EDP30 vs EDP40) and that the ribbon connectors for the keyboard, trackpad, audio and other peripherals are in the same area/match the same number of contacts.
Looking it up online, the replacement keyboard, coolers and replacement panels all seem to be identical for those boards (both panels being 30-pin EDP). Like @itsBrian said, nothing can be guaranteed here as there is no data of anyone attempting the swap for this exact model, but I'd say given the similarities between the boards and replacement parts, you have a much higher chance of success here than most.
Last time I did a full board replacement on a laptop was an old HP DV7-2185DX, so it has been a while.
You're right that "invasive" is probably a bit harsh; difficulty is skill-relative, and you're the only one on the forum with an accurate gauge of your competence working with computer hardware. I meant to highlight that a laptop motherboard swap is not something I would recommend to the average uninitiated user. I didn't intend to be discouraging, so I apologize if it came off that way.
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