Great question. There are many differences. The connection is also very different. SATA and M.2 are not compatible connection types. Other than connection type, speed is the biggest difference. Here's a list of typical speeds for comparison.
I would recommend M.2 SSD over the 2.5". You don't habe to worry about cable management and the speed of M.2's as seen above are typically much faster! The price difference between the two has really minimized compared to how it used to be. Really, there's no reason not to go M.2 if your motherboard supports it. It's a great choice to make!
Comments
The connection is also very different. SATA and M.2 are not compatible connection types. Other than connection type, speed is the biggest difference. Here's a list of typical speeds for comparison.
The price difference between the two has really minimized compared to how it used to be. Really, there's no reason not to go M.2 if your motherboard supports it. It's a great choice to make!