I'd say you've got quite the build here. It'll definitely be able to League with no issue at all.
I'd consider this to be overkill in most ways. You'd easily be able to stream and play League with no issue at all.
Everything is compatible and you've got a bunch of RGB. Looks great to me!
Is there anything that you're looking for recommendations on or any parts you're unsure of?
Are you planning on streaming or doing any other tasks outside a MOBA? Do you play any AAA titles that would be more demanding on your GPU?
I've created a 4K highest settings build that will offer you around 175 FPS.
https://www.microcenter.com/site/content/custom-pc-builder-amd.aspx?load=842e6393-bc12-46da-a00d-3d64f1ef5485
I did leave the fans that you've selected included in the build and tried to keep the white theme that it seemed you were going for while also keeping as much RGB as possible!
I hope this helps, please let me know if you have questions.
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