What you lose out on would depend on where you want to save cost. The easiest area would be the case. There are good cases you can find for about $70 like the Cooler Master NR600, NZXT H510, Lian Li 205, and such. You could also save on the motherboard. The B450 Tomahawk Max is a good board, but you can put a Ryzen 5 3600 in a cheaper motherboard and it will still work fine. There are B450 boards around $80 that should work. You also don't NEED to use an aftermarket cooler. If you're planning to overclock then the Hyper 212 will be a good choice, but the stock cooler is adequate if you leave the CPU at stock settings and don't overclock. I'd also look specifically for the EVGA RTX 2060 KO, which is sold cheaper than other RTX 2060 models that are available, for about $300 typically. Those changes by themselves would save you a fair bit without losing any performance. Between motherboard, case, and GPU it'd be about $130 saved altogether.
The Cooler Master NR600 will have the best airflow due to the mesh front panel, so it would be my personal choice if you're planning on overclocking and care a lot about thermals. A Ryzen 5 3600 + 2060 is a solid mid-range build and you can definitely handle streaming and other multitasking.
Doesn't have the mesh front on that model, but cooling is more than adequate. I've had it for a while and I do overclock my Ryzen 9 3900X. It'll accommodate any air cooler. Up to a 360mm radiator in the front. Good case overall.
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